Reasons to Ask About Tresiba ®

Only Tresiba ® allows adults to vary their daily dosing interval by 8 to 40 hours, providing around­-the-clock control while still maintaining blood sugar control. Taking your insulin at the same time every day is recommended, but if you miss or delay your Tresiba ® dose, simply take it as soon as you can, then return to your normal dosing schedule. Just be sure to leave at least 8 hours between doses.

Tresiba ® in Action

A slow and steady release that works the way the body’s insulin does

For adults, if you miss or delay your Tresiba ® dose, simply take it as soon as you can, then return to your normal dosing schedule. Just be sure to leave at least 8 hours between doses.

FlexTouch ® : Another Reason to Ask About Tresiba ®

The latest in prefilled insulin pen technology from Novo Nordisk

• Tresiba ® FlexTouch ® pen lasts up to 8 weeks once in use if it is refrigerated or kept at room temperature up to 86°F a
• Accurate dosing to 160 units with Tresiba ® U-200
• No push-button extension: Tresiba ® FlexTouch ® has a spring-loaded mechanism that allows the push button to stay in place at any dose. Other prefilled injection pens have a push button that extends when the dose is dialed up
• Also available in a vial

a Opened (in-use) Tresiba ® FlexTouch ® should be refrigerated (36°F to 46°F [2°C to 8°C]) or kept at room temperature (up to 86°F [30°C]), away from direct heat and light.

Tresiba ® Was Studied for Safety

In a large safety study vs Lantus ® in adults with type 2 diabetes and heart disease, Tresiba ® did not increase their risk of major cardiovascular events, such as heart attack, stroke, or death.

Compared to Lantus ® , Tresiba ® also had a lower rate of severe low blood sugar, a possible serious side effect of insulin.

The goal of any diabetes treatment is to lower blood sugar. However, it is possible for your blood sugar to drop too low. Ask your health care provider what blood sugar level is considered low for you.

Learn more about hypoglycemia from the downloadable fact sheet.

Save on Tresiba ®

You may pay as little as $35 or no more than $99 per prescription. b

What is Tresiba ® ?

• Prescription Tresiba ® is a long-acting insulin used to control high blood sugar in adults and children who are 1 year of age and older with diabetes
• Tresiba ® is not for people with diabetic ketoacidosis (increased ketones in the blood or urine)
• It is not known if Tresiba ® is safe and effective in children under 1 year of age
• Tresiba ® is available in 2 concentrations: 200 units/mL and 100 units/mL

Tresiba ® Important Safety Information

Do not share your Tresiba ® FlexTouch ® with other people, even if the needle has been changed. Do not share needles or syringes with another person. You may give other people a serious infection, or get a serious infection from them.

Who should not take Tresiba ® ?

Do not take Tresiba ® if you:

• are having an episode of low blood sugar (hypoglycemia)
• have an allergy to Tresiba ® or any of the ingredients in Tresiba ®

Before taking Tresiba ® , tell your health care provider about all your medical conditions, including if you are:

• pregnant, planning to become pregnant, or are breastfeeding
• taking new prescription or over-the-counter medicines, vitamins, or herbal supplements

Talk to your health care provider about low blood sugar and how to manage it.

How should I take Tresiba ® ?

• Read the Instructions for Use and take Tresiba ® exactly as your health care provider tells you to
• Do not do any conversion of your dose. The dose counter always shows the selected dose in units
• Know the type and strength of insulin you take. Do not change the type of insulin you take unless your health care provider tells you to
• Adults - If you miss or are delayed in taking your dose of Tresiba ® :
  • Take your dose as soon as you remember, then continue with your regular dosing schedule
  • Make sure there are at least 8 hours between doses
  • Call the healthcare provider for information and instructions about checking blood sugar levels more often until the next scheduled dose of Tresiba ®
  • Do not use the exact same spot for each injection.
  • Do not inject where the skin has pits, is thickened, or has lumps.
  • Do not inject where the skin is tender, bruised, scaly or hard, or into scars or damaged skin.

  What should I avoid while taking Tresiba ® ?

  • Do not drive or operate heavy machinery, until you know how Tresiba ® affects you
  • Do not drink alcohol or use prescription or over-the-counter medicines that contain alcohol

  What are the possible side effects of Tresiba ® ?

  Tresiba ® may cause serious side effects that can be life-threatening, including:

  • Low blood sugar (hypoglycemia). Signs and symptoms that may indicate low blood sugar include dizziness, light-headedness, sweating, confusion, headache, blurred vision, slurred speech, shakiness, fast heart beat, anxiety, irritability, mood changes, and hunger.
  • Low potassium in your blood (hypokalemia)
  • Heart failure in some people if taken with thiazolidinediones (TZDs). This can happen even if you have never had heart failure or heart problems. If you already have heart failure, it may get worse while you take TZDs with Tresiba ® . Tell your health care provider if you have any new or worse symptoms of heart failure including shortness of breath, tiredness, swelling of your ankles or feet, and sudden weight gain

  Your insulin dose may need to change because of change in level of physical activity or exercise, increased stress, change in diet, weight gain or loss, or illness.
  

  • Common side effects may include serious allergic reactions (whole body reactions), reactions at the injection site, skin thickening or pits at the injection site (lipodystrophy), itching, rash, swelling of your hands and feet, and weight gain.

  Get emergency medical help if you have trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, or confusion.
  

  What is Tresiba ® ?

  • Prescription Tresiba ® is a long-acting insulin used to control high blood sugar in adults and children who are 1 year of age and older with diabetes
  • Tresiba ® is not for people with diabetic ketoacidosis (increased ketones in the blood or urine)
  • It is not known if Tresiba ® is safe and effective in children under 1 year of age
  • Tresiba ® is available in 2 concentrations: 200 units/mL and 100 units/mL

  Tresiba ® is a prescription medication.
  

  Find help with insulin costs at Novocare.com/letushelp.

  You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

  What is Tresiba ® (insulin degludec) injection 100 U/mL, 200 U/mL?

  What is Tresiba ® ?

  • Prescription Tresiba ® is a long-acting insulin used to control high blood sugar in adults and children who are 1 year of age and older with diabetes
  • Tresiba ® is not for people with diabetic ketoacidosis (increased ketones in the blood or urine)
  • It is not known if Tresiba ® is safe and effective in children under 1 year of age
  • Tresiba ® is available in 2 concentrations: 200 units/mL and 100 units/mL

  Tresiba ® Important Safety Information

  Do not share your Tresiba ® FlexTouch ® with other people, even if the needle has been changed. Do not share needles or syringes with another person. You may give other people a serious infection, or get a serious infection from them.

  Who should not take Tresiba ® ?

  Do not take Tresiba ® if you:

  • are having an episode of low blood sugar (hypoglycemia)
  • have an allergy to Tresiba ® or any of the ingredients in Tresiba ®

  Before taking Tresiba ® , tell your health care provider about all your medical conditions, including if you are:

  • pregnant, planning to become pregnant, or are breastfeeding
  • taking new prescription or over-the-counter medicines, vitamins, or herbal supplements

  Talk to your health care provider about low blood sugar and how to manage it.

  How should I take Tresiba ® ?

  • Read the Instructions for Use and take Tresiba ® exactly as your health care provider tells you to
  • Do not do any conversion of your dose. The dose counter always shows the selected dose in units
  • Know the type and strength of insulin you take. Do not change the type of insulin you take unless your health care provider tells you to
  • Adults - If you miss or are delayed in taking your dose of Tresiba ® :
    • Take your dose as soon as you remember, then continue with your regular dosing schedule
    • Make sure there are at least 8 hours between doses
    • Call the healthcare provider for information and instructions about checking blood sugar levels more often until the next scheduled dose of Tresiba ®
    • Do not use the exact same spot for each injection.
    • Do not inject where the skin has pits, is thickened, or has lumps.
    • Do not inject where the skin is tender, bruised, scaly or hard, or into scars or damaged skin.

    What should I avoid while taking Tresiba ® ?

    • Do not drive or operate heavy machinery, until you know how Tresiba ® affects you
    • Do not drink alcohol or use prescription or over-the-counter medicines that contain alcohol

    What are the possible side effects of Tresiba ® ?

    Tresiba ® may cause serious side effects that can be life-threatening, including:

    • Low blood sugar (hypoglycemia). Signs and symptoms that may indicate low blood sugar include dizziness, light-headedness, sweating, confusion, headache, blurred vision, slurred speech, shakiness, fast heart beat, anxiety, irritability, mood changes, and hunger.
    • Low potassium in your blood (hypokalemia)
    • Heart failure in some people if taken with thiazolidinediones (TZDs). This can happen even if you have never had heart failure or heart problems. If you already have heart failure, it may get worse while you take TZDs with Tresiba ® . Tell your health care provider if you have any new or worse symptoms of heart failure including shortness of breath, tiredness, swelling of your ankles or feet, and sudden weight gain

    Your insulin dose may need to change because of change in level of physical activity or exercise, increased stress, change in diet, weight gain or loss, or illness.
    

    • Common side effects may include serious allergic reactions (whole body reactions), reactions at the injection site, skin thickening or pits at the injection site (lipodystrophy), itching, rash, swelling of your hands and feet, and weight gain.

    Get emergency medical help if you have trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, or confusion.
    

    What is Tresiba ® ?

    • Prescription Tresiba ® is a long-acting insulin used to control high blood sugar in adults and children who are 1 year of age and older with diabetes
    • Tresiba ® is not for people with diabetic ketoacidosis (increased ketones in the blood or urine)
    • It is not known if Tresiba ® is safe and effective in children under 1 year of age
    • Tresiba ® is available in 2 concentrations: 200 units/mL and 100 units/mL

    Tresiba ® is a prescription medication.
    

    Find help with insulin costs at Novocare.com/letushelp.